The primary structure of a short neurotoxin homologue from Dendroaspis polylepis polylepis (Black mamba) venom
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چکیده
منابع مشابه
Black mamba dendroaspis polylepis bite: a case report.
Although very rare in a European context, a bite from the black mamba Dendroaspis polylepis is an event that poses an immediate threat to life. Given the content of neurotoxins in the snake's venom, the mortality of envenomation reaches 100% in almost every case if ventilation is not provided in a timely manner and adequate therapy initiated. The report d...
متن کاملAn Unexpected Case of Black Mamba (Dendroaspis polylepis) Bite in Switzerland
Mambas (genus Dendroaspis) are among the most feared venomous African snakes. Without medical treatment, mamba bites are frequently fatal. First-aid treatment includes lymphatic retardation with the pressure immobilization technique. Medical management comprises continuous monitoring, securing patency of the airway, ensuring adequate ventilation, symptomatic measures, and administration of spec...
متن کاملMuscarinic Toxins from Dendroaspis (Mamba) Venom
Jolkkonen, M., 1996. Muscarinic Toxins from Dendroaspis (Mamba) Venom: Peptides Selective for Subtypes of Muscarinic Acetylcholine Receptors. Acta Univ. Ups., Comprehensive Summaries of Uppsala Dissertations from the Faculty of Science and Technology 183. 52 pp. Uppsala. ISBN 91-554-3675-7 Snake venoms from various mamba species contain peptides which bind to the muscarinic but not to the nicot...
متن کاملIsolation of a Postynaptic Blocker from the Venom of the Green Mamba, Dendroaspis angusticeps
A blocker of postsynaptic acetylcholine receptors was isolated from venom of the Eastern green mamba Dendroaspis angusticeps, by gel filtration, ion-exchange and reverse phase high performance liquid chromatography. The isolated component blocks neuromuscular transmission and responses to exogenously applied acetylcholine in isolated chick biventer cervices preparations. These results suggest t...
متن کاملThe medical threat of mamba envenoming in sub-Saharan Africa revealed by genus-wide analysis of venom composition, toxicity and antivenomics profiling of available antivenoms.
Mambas (genus Dendroaspis) are among the most feared of the medically important elapid snakes found in sub-Saharan Africa, but many facets of their biology, including the diversity of venom composition, remain relatively understudied. Here, we present a reconstruction of mamba phylogeny, alongside genus-wide venom gland transcriptomic and high-resolution top-down venomic analyses. Whereas the g...
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ژورنال
عنوان ژورنال: Suid-Afrikaanse Tydskrif vir Natuurwetenskap en Tegnologie
سال: 1984
ISSN: 2222-4173,0254-3486
DOI: 10.4102/satnt.v3i3.1084